Research
COVID-19 Studies
| Name | Type | Funder | Sponsor | Status | Approval Date |
|---|---|---|---|---|---|
| HORIZON 2 | not available | Janssen Vaccines & Prevention B.V. | Janssen Vaccines & Prevention B.V. | In Setup | not available |
| CORONAVIT | Interventional | PHARMA NORD (UK) LIMITED | Queen Mary University of London | Closed | not available |
| CLARITY | Observational | F. Hoffmann-La Roche Ltd; Hull University Teadhing Hospitals NHS Trust | Royal Devon and Exeter NHS Foundation Trust | Closed | not available |
| AERATOR | Observational | NIHR/UKRI | North Bristol NHS Trust | Open | not available |
| ComFluCov | Interventional | NIHR Central Commissioning Facility (CCF) | UNIVERSITY HOSPITALS BRISTOL AND WESTON NHS FOUNDATION TRUST | Open | 26-Mar-21 |
| Comparing COVID-19 Vaccine Schedule Combinations - Stage 2 (Com-COV2) | Interventional | DEPARTMENT FOR BUSINESS, ENERGY AND INDUSTRIAL STRATEGY | University of Oxford | In Setup | 25-Mar-21 |
| PROTECT V | Interventional | LIFEARC | CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST | Open | 17-Mar-21 |
| HEAL-COVID trial | Interventional | National Institute for Health Research (NIHR) | CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST | In Setup | 17-Mar-21 |
| Children & young people with Long Covid (CLoCk) study | Observational | NIHR / UKRI | GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST | In Setup | 10-Mar-21 |
| OCTAVE | not available | NIHR / UKRI | University of Birmingham | Open | 01-Mar-21 |
| A phase II study of a candidate COVID-19 vaccine in children (COV006) | Both | NIHR Central Commissioning Facility (CCF) | not available | Open | 17-Feb-21 |
| Study of the safety of & response to a COVID-19 vaccine in pregnancy | Interventional | Janssen-Cilag Ltd | Janssen-Cilag Ltd | In Setup | 17-Feb-21 |
| SPIKE-1 | Interventional | LIFEARC | Cancer Research UK | Open | 01-Feb-21 |
| CO@h patient experience study (V1.0) | Observational | NIHR | University College London | Open | 29-Jan-21 |
| SG016 Home Study | Interventional | not available | Synairgen Research Limited | Closed | 13-Jan-21 |
| A Randomized, Double-blind, Placebo-controlled Phase 2a Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2.S in Healthy Adults Aged 18 to 55 Years Inclusive and Adults Aged 65 Years and Older and to Evaluate 2 Dose Levels of A | Interventional | not available | Janssen | Open | 13-Jan-21 |
| Non-inferiority study comparing immunogenicity against COVID-19 of VLA2001 with [ACTIVE COMPARATOR] | Interventional | not available | Valneva | In Setup | 13-Jan-21 |
| Com-COV: Comparing COVID-19 Vaccine Schedule Combinations | Interventional | Department for Business, Energy and Industrial Strategy | University of Oxford | Closed | 13-Jan-21 |
| COVID-19 Vacc Maternal Immunisation | Interventional | Pfizer Inc. | Pfizer Inc. | In Setup | 13-Jan-21 |
| CoVLP | Interventional | Medicago | Medicago | In Setup | 21-Dec-20 |
| COVID-CNS | Observational | MRC / UKRI | University of Liverpool | Open | 21-Dec-20 |
| PRONTO | Both | NIHR | University of Liverpool | Open | 08-Dec-20 |
| CCP-Cancer UK | Observational | CLATTERBRIDGE CANCER CHARITY; NIHR / UKRI | THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST | Open | 06-Nov-20 |
| SARS-COV-2 Virus Vaccine (VLA2001) against COVID-19 | Interventional | Valneva | Valneva | Closed | 29-Oct-20 |
| STORM CHASER | Interventional | AstraZeneca | AstraZeneca | Closed | 19-Oct-20 |
| ADAPT-Sepsis Trial | Interventional | NIHR | University of Manchester | Open | 19-Oct-20 |
| Phase III trial of inhaled anti-viral (SNG001) for SARS-CoV-2 | Interventional | Synairgen Research Limited | Synairgen Research Limited | Open | 14-Oct-20 |
| RECAP | Observational | Oxford team: UKRI. Imperial team: Community Jameel (philanthropic) fund | Imperial College London | Open | 14-Oct-20 |
| PROVENT | Interventional | AstraZeneca | AstraZeneca | Closed | 09-Oct-20 |
| Characterisation of COVID-19 long-term immune response | Observational | Medical Research Council | University of Bristol | Closed | 01-Oct-20 |
| A Phase 3 COVID-19 Vaccine Study | Interventional | Janssen-Cilag Ltd | Janssen-Cilag Ltd | Closed | 28-Aug-20 |
| A trial to evaluate SARS-CoV-2 Recombinant Nanoparticle vaccine | Interventional | NOVAVAX, INC. | NOVAVAX, INC. | Closed | 28-Aug-20 |
| COVID-19 Infection Survey | Observational | Office for National Statistics | University of Oxford | Open | 20-Aug-20 |
| COVID-19 Germ Defence Implementation | Interventional | NIHR/UKRI | University of Bristol | Closed | 10-Aug-20 |
| NHS CHECK | Observational | NIHR/UKRI | King's College London | Closed | 05-Aug-20 |
| CoMMinS | Observational/Interventional | NIHR/UKRI | University of Bristol | Open | 05-Aug-20 |
| UK-REACH | Observational | NIHR/UKRI | University of Leicester | Open | 20-Jul-20 |
| TraCK: Transmission of COVID-19 in Kids | Observational | Action Medical Research | Imperial College of Science, Technology and Medicine | Open | 16-Jul-20 |
| Humoral Immune Correlates for COVID19 | Interventional | NIHR/UKRI | Royal Papworth Hospital NHS Foundation Trust | Open | 01-Jul-20 |
| UK Coronavirus Immunology Consortium (CIC) | Observational | NIHR/UKRI | University of Birmingham | Open | 01-Jul-20 |
| PHOSP-COVID | Observational | NIHR/UKRI | University of Leicester | Open | 01-Jul-20 |
| COVID-HEART | Observational | not available | Leeds Teaching Hospitals NHS Trust | Closed | 04-Jun-20 |
| C-MORE Capturing MultiORgan Effects of COVID-19 | Observational | NIHR/UKRI | University of Oxford | Open | 04-Jun-20 |
| VIVALDI | Observational | Department of Health and Social Care | University College London | Open | 02-Jun-20 |
| BASIL+ | Both | NIHR Central Commissioning Facility (CCF) | Tees, Esk and Wear Valleys NHS Foundation Trust | Open | 28-May-20 |
| BASIL-C19 | Interventional | NIHR | Tees, Esk and Wear Valleys NHS Foundation Trust | Closed | 28-May-20 |
| REPROVIDE | Interventional | NIHR | University of Bristol | Open | 28-May-20 |
| COVAC 1 | Interventional | NIHR/UKRI | Imperial College London | Closed | 20-May-20 |
| SIREN - SARS-COV2 immunity and reinfection evaluation | Observational | Public Health England | Public Health England | Closed | 18-May-20 |
| CATALYST | Interventional | not available | University of Birmingham | Closed | 11-May-20 |
| TACTIC-R | Interventional | Ely Lilly and Company; Alexion Pharmaceuticals | Cambridge University Hospitals NHS Foundation Trust | Open | 11-May-20 |
| DEFINE | Interventional | not available | not available | Suspended | 11-May-20 |
| COG-UK HOCI | Interventional | UK Research and Innovation (UKRI) | University College London | Open | 11-May-20 |
| OSCAR | Interventional | GlaxoSmithKline | GlaxoSmithKline | Closed | 07-May-20 |
| MERMAIDS - ARI | Observational | European Commission | University of Oxford | Open | 07-May-20 |
| FALCON C-19 | Observational | NIHR/UKRI | Manchester University NHS Foundation Trust | Open | 04-May-20 |
| RAPTOR C-19 | Observational | NIHR/UKRI | University of Oxford | Open | 04-May-20 |
| FALCON C-19 (Workstream B) | Observational | NIHR / UKRI | Manchester University NHS Foundation Trust | Open | 04-May-20 |
| Investigating a Vaccine Against COVID-19 (COV002) | Interventional | NIHR/UKRI | University of Oxford | Closed | 30-Apr-20 |
| STOP-COVID19 | Interventional | Insmed Inc | University of Dundee | Closed | 21-Apr-20 |
| ACCORD | Interventional | BERGENBIO AS | UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST | Open | 21-Apr-20 |
| Neonatal complications of coronavirus disease (COVID-19) | Observational | NIHR | University of Oxford | Open | 21-Apr-20 |
| Virus Watch | Observational | NIHR/UKRI | University College London | Open | 18-Apr-20 |
| Pregnancy and Neonatal Outcomes in COVID-19 | Observational | NIHR/UKRI | Imperial College of Science, Technology and Medicine | Open | 18-Apr-20 |
| RECOVERY - Respiratory Support | Interventional | Department of Health and Social Care | University of Warwick | Open | 13-Apr-20 |
| DeVENT | Interventional | European Commission | Imperial College of Science, Technology and Medicine | Open | 13-Apr-20 |
| CANCOVID | Interventional | Novartis | Novartis | Closed | 06-Apr-20 |
| RUXCOVID | Interventional | Novartis | Novartis | Closed | 06-Apr-20 |
| ILIAD 7 | Interventional | RevImmune | RevImmune | Open | 06-Apr-20 |
| What's the STORY | Observational | NIHR/UKRI | University of Oxford | Open | 06-Apr-20 |
| Repair of ARDS by Stromal Cell Administration (REALIST) | Interventional | Public Health Agency for Northern Ireland; Wellcome Trust | Belfast Health & Social Care Trust | Open | 02-Apr-20 |
| GenOMICC | Observational | Wellcome Trust | NHS Lothian | Open | 02-Apr-20 |
| Coronavirus infection in immunosuppressed children | Observational | British Paediatric Allergy, Immunity and Infection Group | UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST | Closed | 02-Apr-20 |
| DIAMONDS SEARCH | Observational | European Commission | Imperial College of Science, Technology and Medicine | Open | 02-Apr-20 |
| SARS-CoV-2 infection | Interventional | SYNAIRGEN RESEARCH LIMITED | SYNAIRGEN RESEARCH LIMITED | Closed | 30-Mar-20 |
| COPCOV trial | Interventional | Wellcome Trust | University of Oxford | Closed | 30-Mar-20 |
| REMAP-CAP | Interventional | European Commission | University Medical Centre Utrecht (Netherlands) | Open | 27-Mar-20 |
| Adaptive COVID-19 Treatment Trial (ACTT) | Interventional | National Institutes of Health (NIH), United States | University of Minnesota (USA) | Closed | 27-Mar-20 |
| A study to evaluate TCZ in patients with severe COVID-19 Pneumonia | Interventional | F. Hoffmann-La Roche Ltd | F. Hoffmann-La Roche Ltd | Closed | 26-Mar-20 |
| 5774 Safety & Antiviral Activity of Remdesivir for moderate COVID-19 | Interventional | Gilead Sciences Inc | Gilead Sciences Inc | Closed | 25-Mar-20 |
| 5773 Safety and Antiviral Activity of Remdesivir for severe COVID-19 | Interventional | Gilead Sciences Inc | Gilead Sciences Inc | Closed | 25-Mar-20 |
| The PRIEST Study | Observational | NIHR | SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST | Closed | 20-Mar-20 |
| FLU-CATs : Evaluation and refinement of pandemic influenza community assessment tools | Observational | NIHR | University of Liverpool | Open | 20-Mar-20 |
| UKOSS: Pandemic Influenza in Pregnancy | Observational | NIHR | University of Oxford | Open | 20-Mar-20 |
| A phase I/II trial of a candidate COVID-19 vaccine (COV001) | Interventional | NIHR/UKRI | University of Oxford | Closed | 11-Mar-20 |
| RECOVERY trial | Interventional | NIHR/UKRI | University of Oxford | Open | 11-Mar-20 |
| PRINCIPLE | Interventional | NIHR/UKRI | University of Oxford | Open | 11-Mar-20 |
| Rapid development of manufacturing processes for future production of adenovirus-vectored COVID19 vaccine at million-dose scale | Pre-clinical | NIHR/UKRI | University of Oxford | not available | 11-Mar-20 |
| nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses including SARS-CoV-2 | Pre-clinical | NIHR/UKRI | not available | Possible pre-clinical study | 11-Mar-20 |
| Repurposing FDA-Approved Drugs for Treatment of 2019-nCoV-induced Disease | Pre-clinical | NIHR/UKRI | Queens University Belfast | not available | 11-Mar-20 |
| Clinical Characterisation Protocol (CCP) for Severe Emerging Infection | Observational | Wellcome Trust | University of Oxford | Open | 24-Jan-20 |